Treadmill running induces satellite cell activation in diabetic mice

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Treadmill running induces satellite cell activation in diabetic mice

Skeletal muscle-derived stem cells, termed as satellite cells, play essential roles in regeneration after muscle injury in adult skeletal muscle. Diabetes mellitus (DM), one of the most common metabolic diseases, causes impairments of satellite cell function. However, the studies of the countermeasures for the DM-induced dysfunction of satellite cells have been poor. Here, we investigated the e...

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Synergistic Effect Of Treadmill Exercise And Green Tea Extract On Cutaneous wound Healing In Diabetic Mice

Aim and Background: In the study , synergistic effect of green tea (camellia sinesis) extract and treadmill aerobic exercise on wound healing in streptozotocin induced diabetic mice has been investigated.   Material and methods: The number of 50 male mice with the approximately weight of 30-35 gram health and adult are put in 5 groups: non diabetic – immobile , diabetic - immobile, diabetic...

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Treadmill running improves hindlimb arteriolar endothelial function in type 1 diabetic mice as visualized by X-ray microangiography

BACKGROUND Vascular function is impaired in patients with diabetes, however diabetic vascular dysfunction is ameliorated by exercise training. We aimed to clarify which hindlimb arterial segments are affected by treadmill running in the hindlimbs of streptozocin-induced type 1 diabetic mice in vivo. METHODS Mice were divided into 3 groups; healthy control, diabetic control, and diabetic-runni...

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Running Head: Satellite Cell Proliferation and Differentiation

Age-related changes in satellite cell proliferation and differentiation during rapid growth of porcine skeletal muscle were examined. Satellite cells were isolated from hindlimb muscles of pigs at 1, 7, 14, and 21 weeks of age (4 animals/age group). Satellite cells were separated from cellular debris using Percoll gradient centrifugation, and adsorbed to glass coverslips for fluorescent immunos...

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Estrogen influences satellite cell activation and proliferation following downhill running in rats.

To investigate the influence of estrogen on postexercise muscle repair processes, we examined the effects of estrogen supplementation (0.25-mg pellet) on numbers of myofibers positive for markers of total, activated, and proliferating satellite cells in rat skeletal muscles 72 h following downhill running. Ovariectomized female rats (n = 44) were divided into four groups (n = 11 per group): sha...

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ژورنال

عنوان ژورنال: Biochemistry and Biophysics Reports

سال: 2016

ISSN: 2405-5808

DOI: 10.1016/j.bbrep.2016.07.004